Description

5-Pyrimidinecarboxaldehyde, 2-Amino-4,6-Difluoro- (9Ci) is a high-value, fluorinated pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines a reactive aldehyde group with amino and fluoro substituents, enabling precise modifications for creating novel compounds. This building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals. The compound, identified by CAS number 500891-31-6, is supplied to meet the stringent demands of modern R&D and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in antiviral, anticancer, and CNS-targeted therapeutic research.
• Agrochemical Development: Used to construct active ingredients for next-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the difluoropyrimidine core.
• Material Science Research: Serves as a building block for creating specialized ligands, functional polymers, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects requiring high-purity, complex heterocyclic aldehydes.

Basic Information

Product Name	5-Pyrimidinecarboxaldehyde, 2-Amino-4,6-Difluoro- (9Ci)
CAS No.	500891-31-6
Molecular Formula	C5H3F2N3O
Molecular Weight	159.10 g/mol
Synonyms	2-Amino-4,6-difluoropyrimidine-5-carboxaldehyde; 2-Amino-4,6-difluoro-5-pyrimidinecarboxaldehyde; 4,6-Difluoro-2-aminopyrimidine-5-carbaldehyde; 5-Formyl-2-amino-4,6-difluoropyrimidine; 2-Amino-4,6-difluoropyrimidine-5-carbaldehyde; 500891-31-6; 2-Amino-4,6-difluoro-5-formylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxaldehyde, 2-Amino-4,6-Difluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality ensures the material meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store the product at 2-8°C under an inert atmosphere. Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.