Description

(R)-Boc-3 4-Dimethoxy-β-Phe-Oh is a chiral, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and dimethoxy-substituted phenyl side chain. This compound serves as a critical building block in the synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry and side-chain functionality. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), drug discovery programs, and advanced material science.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based therapeutics and bioactive molecules.
• Drug Discovery & Medicinal Chemistry: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Peptide Synthesis: Essential building block in solid-phase and solution-phase peptide synthesis (SPPS) for introducing modified phenylalanine residues.
• API Development: Intermediate in the multi-step synthesis of complex target molecules for clinical trials and commercial production.
• Bioconjugation & Probe Development: Useful for creating labeled peptides or affinity probes for biochemical and diagnostic applications.
• Academic & Industrial Research: Serves as a standard or custom reagent for methodological development in organic and bioorganic chemistry.

Basic Information

Product Name	(R)-Boc-3 4-Dimethoxy-β-Phe-Oh
CAS No.	500788-93-2
Molecular Formula	C₁₆H₂₃NO₆
Molecular Weight	325.36 g/mol
Synonyms	(R)-3-(3,4-Dimethoxyphenyl)-2-((tert-butoxycarbonyl)amino)propanoic Acid; (R)-2-((tert-Butoxycarbonyl)amino)-3-(3,4-dimethoxyphenyl)propanoic Acid; Boc-3,4-Dimethoxy-D-β-homo-phenylalanine; Boc-(R)-3,4-Dimethoxy-β-homo-Phe-OH; (R)-Boc-3,4-Dimethoxy-β-homophenylalanine; N-Boc-3,4-dimethoxy-D-β-homophenylalanine; N-(tert-Butoxycarbonyl)-3,4-dimethoxy-D-β-homophenylalanine
EINECS	Contact for details

Quality Control

Our (R)-Boc-3 4-Dimethoxy-β-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.