Description

Boc-β-(R)-4-Methoxyphenylalanine is a protected, non-natural amino acid derivative of significant importance in advanced organic synthesis. This chiral building block is essential for the construction of complex peptide-based molecules and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers in the development of novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for incorporating a protected, methoxy-substituted phenylalanine residue.
• Protease Inhibitor Development: Serves as a critical component in the design and synthesis of inhibitors targeting specific proteolytic enzymes.
• Chemical Biology Probes: Employed in the creation of labeled or modified peptides for studying protein-protein interactions and cellular pathways.
• Asymmetric Synthesis: Acts as a starting material or intermediate in the asymmetric synthesis of more complex chiral molecules.
• Academic & Industrial R&D: Fundamental building block in research laboratories for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Boc-β-(R)-4-Methoxyphenylalanine
CAS No.	500788-87-4
Molecular Formula	C15H21NO5
Molecular Weight	295.33 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoic acid; Boc-(R)-β-(4-Methoxyphenyl)alanine; N-Boc-β-(R)-4-Methoxyphenylalanine; tert-Butyloxycarbonyl-(R)-β-(4-methoxyphenyl)alanine; N-(tert-Butoxycarbonyl)-β-(R)-4-methoxyphenylalanine; Boc-β-(R)-4-MeO-Phe-OH; Boc-(R)-4-Methoxy-β-phenylalanine
EINECS	Contact for details

Quality Control

Our Boc-β-(R)-4-Methoxyphenylalanine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to industry-standard analytical protocols to guarantee product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.