Description

2-Chloro-6-(2-Hydroxybenzylamino)-9-Isopropylpurine is a specialized purine derivative, a key chemical scaffold in medicinal chemistry and pharmaceutical research. This compound is valued for its role as a versatile synthetic intermediate in the development of novel therapeutic agents, particularly kinase inhibitors. It is essential for research and development teams in the pharmaceutical, biotechnology, and fine chemical synthesis sectors seeking to explore new bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of targeted kinase inhibitors and other purine-based drug candidates.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic studies and signal transduction pathway analysis.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for the production of high-value, complex organic molecules.
• Academic Research: Utilized in university and institutional labs for investigating novel chemical biology mechanisms and drug discovery projects.

Basic Information

Product Name	2-Chloro-6-(2-Hydroxybenzylamino)-9-Isopropylpurine
CAS No.	500568-72-9
Molecular Formula	C15H16ClN5O
Molecular Weight	317.77 g/mol
Synonyms	9-Isopropyl-2-chloro-6-[(2-hydroxyphenyl)methylamino]purine; 2-Chloro-6-[(2-hydroxybenzyl)amino]-9-(1-methylethyl)-9H-purine; 2-Chloro-6-(2-hydroxybenzylamino)-9-isopropyl-9H-purine; 9H-Purine, 2-chloro-6-[(2-hydroxybenzyl)amino]-9-(1-methylethyl)-; N-(2-Hydroxybenzyl)-2-chloro-9-isopropyladenine; Kinase Inhibitor Intermediate CK-101; Purine Derivative 500568-72-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(2-Hydroxybenzylamino)-9-Isopropylpurine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.