Description

6-Amino-2-chloropyrimidine-4-carboxamide is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific pyrimidine-based functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of modern herbicides, fungicides, and plant growth regulators that require a chlorinated pyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for the development of organic electronic materials, ligands for metal-organic frameworks (MOFs), or specialty polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or non-GMP conditions.

Basic Information

Product Name	6-Amino-2-chloropyrimidine-4-carboxamide
CAS No.	500352-09-0
Molecular Formula	C5H5ClN4O
Molecular Weight	172.57 g/mol
Synonyms	2-Chloro-6-aminopyrimidine-4-carboxamide; 4-Carbamoyl-6-amino-2-chloropyrimidine; 6-Amino-2-chloro-4-pyrimidinecarboxamide; 2-Chloro-4-carbamoylpyrimidin-6-amine; 6-Amino-2-chloro-pyrimidine-4-carboxylic acid amide; 2-Chloro-6-amino-pyrimidine-4-carboxylic acid amide; 4-Pyrimidinecarboxamide, 6-amino-2-chloro-
EINECS	Contact for details

Quality Control

Our 6-Amino-2-chloropyrimidine-4-carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), related substances, and physical characteristics is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.