Description

4-Pyrimidinecarboxylicacid,2-Amino-1,6-Dihydro-5-Nitro-6-Oxo-(9Ci) CAS NO 500309-09-1 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine carboxylic acid structure. This compound is essential for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for life sciences applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those targeting specific enzymes or receptors.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new chemical entities with potential therapeutic activity.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies investigating enzyme inhibition, nucleotide analog synthesis, and other biochemical pathways.
• Agrochemical Development: Potential use as an intermediate in the research and synthesis of novel crop protection agents.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and methodological studies.

Basic Information

Product Name	4-Pyrimidinecarboxylicacid,2-Amino-1,6-Dihydro-5-Nitro-6-Oxo-(9Ci)
CAS No.	500309-09-1
Molecular Formula	C5H4N4O5
Molecular Weight	200.11 g/mol
Synonyms	2-Amino-5-nitro-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid; 2-Amino-5-nitrouracil-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 2-amino-1,6-dihydro-5-nitro-6-oxo-; 2-Amino-5-nitroorotic acid; 5-Nitroorotic acid, 2-amino-; 2-Amino-5-nitrouracil-4-carboxylate; 5-Nitro-2-aminoorotic acid; 2-Amino-5-nitro-6-oxo-1H-pyrimidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Pyrimidinecarboxylicacid,2-Amino-1,6-Dihydro-5-Nitro-6-Oxo-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.