Description

4-Amino-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6(7H)-One is a high-purity heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought by research institutions and pharmaceutical manufacturers developing novel therapeutic agents, especially kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of purine analog-based active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Core scaffold for the development and optimization of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization during drug discovery.
• Biochemical Research: Serves as a reference standard or substrate analog in enzymatic and biochemical assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry and pharmacology studies.

Basic Information

Item	Details
Product Name	4-Amino-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6(7H)-One
CAS No.	500282-71-3
Molecular Formula	C7H9N5O
Molecular Weight	179.18 g/mol
Synonyms	4-Amino-1-methyl-1,7-dihydro-6H-pyrazolo[3,4-d]pyrimidin-6-one; 1-Methyl-4-amino-1H-pyrazolo[3,4-d]pyrimidin-6(7H)-one; 6H-Pyrazolo[3,4-d]pyrimidin-6-one, 4-amino-1,7-dihydro-1-methyl-; 4-Amino-1-methyl-6H-pyrazolo[3,4-d]pyrimidin-6-one; 4-Amino-1-methyl-7H-pyrazolo[3,4-d]pyrimidin-6-one; 1-Methyl-4-aminopyrazolo[3,4-d]pyrimidin-6-one
EINECS	Contact for details

Quality Control

Our 4-Amino-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6(7H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.