Description

n-Cyclohexyl-3-Fluorobenzylamine is a high-purity fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure imparts desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom and amine functionality can enhance bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, resins, and functional materials that require fluorinated amine components.
• Chemical Biology Probes: Useful for creating fluorescent tags, affinity probes, and other tools for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	n-Cyclohexyl-3-Fluorobenzylamine, 97%
CAS No.	500221-71-6
Molecular Formula	C13H18FN
Molecular Weight	207.29 g/mol
Synonyms	N-Cyclohexyl-1-(3-fluorophenyl)methanamine; 1-(3-Fluorobenzyl)cyclohexanamine; 3-Fluoro-N-(cyclohexylmethyl)benzenemethanamine; (3-Fluorobenzyl)cyclohexylamine; N-[(3-Fluorophenyl)methyl]cyclohexanamine; Benzenemethanamine, 3-fluoro-N-(cyclohexylmethyl)-; Cyclohexyl(3-fluorobenzyl)amine
EINECS	Contact for details

Quality Control

Our n-Cyclohexyl-3-Fluorobenzylamine is produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure the specified 97% minimum purity and identity are met. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request for every shipment, providing full traceability and compliance documentation for your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere such as nitrogen to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.