Description

Methyl 4-({[(4-{[(2,6-Dimethoxy-4-Pyrimidinyl)Amino]Sulfonyl}Phenyl)Amino]Carbonothioyl}Amino)-4-Oxobutanoate is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture designed for targeted synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the creation of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the synthesis of complex heterocyclic compounds and potential drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new therapeutic molecules.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex sulfonamide and pyrimidine-based compounds.
• Bioconjugation & Probe Development: Potential use in developing chemical probes for biochemical assays due to its reactive functional groups.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry projects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	Methyl 4-({[(4-{[(2,6-Dimethoxy-4-Pyrimidinyl)Amino]Sulfonyl}Phenyl)Amino]Carbonothioyl}Amino)-4-Oxobutanoate
CAS No.	500201-28-5
Molecular Formula	C18H20N6O7S2
Molecular Weight	496.52 g/mol
Synonyms	Methyl 4-({[(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)amino]carbonothioyl}amino)-4-oxobutanoate; Methyl 4-({[(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)amino]carbonothioyl}amino)butanedioate; 4-({[(4-{[(2,6-Dimethoxy-4-pyrimidinyl)amino]sulfonyl}phenyl)amino]carbonothioyl}amino)-4-oxobutanoic acid methyl ester; Butanedioic acid, 4-[[[[[4-[(2,6-dimethoxy-4-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]amino]-, 1-methyl ester; CAS 500201-28-5
EINECS	Contact for details

Quality Control

Our Methyl 4-({[(4-{[(2,6-Dimethoxy-4-Pyrimidinyl)Amino]Sulfonyl}Phenyl)Amino]Carbonothioyl}Amino)-4-Oxobutanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.