Description

4-Chloro-5-(2-Chloro-Benzyl)-6-Methyl-Pyrimidin-2-Ylamine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides, fungicides, and insecticides.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of complex target molecules for clinical and commercial production.
• Material Science: Potential intermediate for creating specialty polymers or organic electronic materials with specific functionalities.

Basic Information

Product Name	4-Chloro-5-(2-Chloro-Benzyl)-6-Methyl-Pyrimidin-2-Ylamine
CAS No.	500157-71-1
Molecular Formula	C₁₂H₁₁Cl₂N₃
Molecular Weight	268.14 g/mol
Synonyms	2-Amino-4-chloro-5-[(2-chlorophenyl)methyl]-6-methylpyrimidine; 4-Chloro-5-(2-chlorobenzyl)-6-methyl-2-pyrimidinamine; 5-(2-Chlorobenzyl)-4-chloro-6-methylpyrimidin-2-amine; 2-Pyrimidinamine, 4-chloro-5-[(2-chlorophenyl)methyl]-6-methyl-; 4-Chloro-5-(2-chloro-benzyl)-6-methyl-pyrimidin-2-ylamine; CAS 500157-71-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-(2-Chloro-Benzyl)-6-Methyl-Pyrimidin-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.