Description

2,4(1H,3H)-Pyrimidinedione, 5-Ethynyl- (9Ci) is a specialized pyrimidine derivative featuring an ethynyl substituent, a key structural motif for advanced chemical synthesis. This compound serves as a versatile and high-value building block in medicinal chemistry and materials science, enabling the construction of complex molecular architectures. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside analogs and other potential therapeutic agents targeting viral and oncological diseases.
• Agrochemical Research: Used in developing novel pesticides and herbicides by acting as a core scaffold for bioactive molecules.
• Chemical Biology Probe: The ethynyl group allows for bioorthogonal labeling (e.g., via click chemistry) to study biological processes and protein interactions.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthetic chemistry projects.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione, 5-Ethynyl- (9Ci)
CAS No.	59989-18-3
Molecular Formula	C6H4N2O2
Molecular Weight	136.11 g/mol
Synonyms	5-Ethynyluracil; 5-Ethynyl-2,4-dihydroxypyrimidine; 5-Ethynylpyrimidine-2,4(1H,3H)-dione; NSC 163038; 5-Ethynyl-1H-pyrimidine-2,4-dione; 2,4-Dihydroxy-5-ethynylpyrimidine; 5-Ethynyl-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Every batch of 2,4(1H,3H)-Pyrimidinedione, 5-Ethynyl- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports applications requiring high-purity intermediates under GMP-like controls for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.