Description

5-Pyrimidinamine, 2-(1,1-Dimethylethyl)- (9Ci) is a substituted pyrimidine derivative, a versatile heterocyclic amine building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce sterically hindered tert-butylamino functionality into pyrimidine-based systems.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-donor ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and functional polymers requiring tailored electronic properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Pyrimidinamine, 2-(1,1-Dimethylethyl)- (9Ci)
CAS No.	59950-55-9
Molecular Formula	C8H13N3
Molecular Weight	151.21 g/mol
Synonyms	2-tert-Butylpyrimidin-5-amine; 2-(tert-Butyl)pyrimidin-5-amine; 5-Amino-2-tert-butylpyrimidine; 2-tert-Butyl-5-pyrimidinamine; 5-Pyrimidinamine, 2-(1,1-dimethylethyl)-; 2-(tert-Butyl)-5-aminopyrimidine; 2-tert-Butyl-5-aminopyrimidine; 5-Amino-2-(1,1-dimethylethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinamine, 2-(1,1-Dimethylethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.