Description

5-Bromo-2-tert-Butyl-Pyrimidine-4-Carboxylic Acid is a high-purity, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and sterically hindered structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its pyrimidine core.
• Material Science Research: Serves as a precursor for creating specialized ligands, monomers, or functional materials requiring a brominated heterocyclic component.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in bioconjugation chemistry due to its reactive bromine atom and carboxylic acid functionality.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	5-Bromo-2-tert-Butyl-Pyrimidine-4-Carboxylic Acid
CAS No.	59950-52-6
Molecular Formula	C9H11BrN2O2
Molecular Weight	259.10 g/mol
Synonyms	5-Bromo-2-(tert-butyl)pyrimidine-4-carboxylic acid; 2-tert-Butyl-5-bromopyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 5-bromo-2-(1,1-dimethylethyl)-; 5-Bromo-2-tert-butyl-4-pyrimidinecarboxylic acid; 5-Bromo-2-(1,1-dimethylethyl)-4-pyrimidinecarboxylic acid; 5-Bromo-2-tert-butylpyrimidine-4-carboxylic acid; 59950-52-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-tert-Butyl-Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis projects, we can tailor quality protocols to meet specific GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.