Description

4-o-(2,6-Diamino-2,6-Dideoxy-α-D-Glucopyranosyl)-5-o-β-D-Xylofuranosyl-n-[(S)-4-Amino-2-Hydroxy-1-Oxobutyl]-D-Streptamine is a structurally complex aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel antibacterial agents, particularly in the exploration of next-generation antibiotics targeting resistant bacterial strains. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel aminoglycoside antibiotics.
• Research & Development: Used as a reference standard in analytical method development, pharmacokinetic studies, and mechanism of action research.
• Biochemical Research: Employed in studies investigating bacterial ribosome interaction and the molecular basis of antibiotic resistance.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial building block in the multi-step synthesis of complex therapeutic agents.
• Quality Control: Utilized as a certified reference material (CRM) for the identification and assay of related pharmaceutical products.

Basic Information

Product Name	4-o-(2,6-Diamino-2,6-Dideoxy-α-D-Glucopyranosyl)-5-o-β-D-Xylofuranosyl-n-[(S)-4-Amino-2-Hydroxy-1-Oxobutyl]-D-Streptamine
CAS No.	59867-75-3
Molecular Formula	C22H43N5O13
Molecular Weight	585.61 g/mol
Synonyms	4''-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-β-D-xylofuranosyl-N-[(S)-4-amino-2-hydroxy-1-oxobutyl]-D-streptamine; 4''-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-β-D-xylofuranosylparomamine; Antibiotic XK 62-2; XK-62-2; Paromamine derivative; Aminoglycoside intermediate; (2S)-4-Amino-2-hydroxy-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-[(2R,3R,4R,5R)-3,5-diamino-4,6-dihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]butanamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.