Description

Ac-D-Pro-Oh CAS NO 59785-68-1 is a high-purity, protected amino acid derivative, specifically the N-acetylated form of D-proline. This compound is a critical chiral building block in the synthesis of complex peptides and pharmaceutical intermediates, offering precise control over stereochemistry and molecular structure. It is essential for research and production in the pharmaceutical, biotechnology, and advanced organic synthesis sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce D-proline residues, which can enhance peptide stability and biological activity.
• Proteomics Research: Serves as a standard or reagent in biochemical research for studying enzyme specificity and protein structure-function relationships.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for asymmetric synthesis.
• Cosmetic Peptides: A potential ingredient in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Item	Details
Product Name	Ac-D-Pro-Oh
CAS No.	59785-68-1
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	N-Acetyl-D-proline; (R)-1-Acetylpyrrolidine-2-carboxylic acid; D-Proline, N-acetyl-; Ac-D-Pro-OH; N-Acetyl-(R)-proline; Ac-D-Pro; N-Acetyl-D-proline, 98+%; UNII-4J8Z4P49PJ
EINECS	Contact for details

Quality Control

Our Ac-D-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.