Description

H-His-Pro-Nh2 2 HBr is a high-purity, protected dipeptide derivative supplied as a hydrobromide salt. This compound serves as a critical building block in the synthesis of complex peptides and peptidomimetics, offering researchers and manufacturers precise control over molecular structure. It is primarily utilized by the pharmaceutical, biotechnology, and advanced research sectors for applications in drug discovery, biochemical research, and the development of therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or inhibitor analog to investigate biological pathways.
• Peptide Library Construction: An essential component in solid-phase and solution-phase peptide synthesis for creating diverse compound libraries for screening.
• Neuroscience Research: Investigated for its potential role in neurological processes due to the histidine and proline residues.
• Cosmetic Peptide Synthesis: Employed in the development of specialized bioactive peptides for advanced skincare formulations.
• Standards and Reference Materials: Serves as a certified reference standard for analytical method development and quality control in peptide analysis.

Basic Information

Product Name	H-His-Pro-Nh2 2 HBr
CAS No.	59760-04-2
Molecular Formula	C11H18N6O2 • 2HBr
Molecular Weight	466.13 g/mol
Synonyms	Histidyl-Prolinamide Dihydrobromide; L-Histidyl-L-prolinamide Dihydrobromide; H-His-Pro-NH2 • 2HBr; His-Pro-NH2 Hydrobromide; Histidylprolinamide Dihydrobromide; 59760-04-2; L-Histidyl-L-proline amide dihydrobromide; Histidyl-Pro Amide 2HBr
EINECS	Contact for details

Quality Control

Our H-His-Pro-Nh2 2 HBr is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-L isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Assay (by titration)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.