Description

Butikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. This compound is valued for its potent activity against a broad spectrum of Gram-negative and some Gram-positive bacteria, including strains resistant to other antibiotics. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the formulation of injectable antibiotic treatments.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for systemic bacterial infections.
• Veterinary Medicine: Used in the development of treatments for bacterial infections in livestock and companion animals.
• Research & Development: Serves as a key reference standard and intermediate in microbiological and pharmacological research.
• Combination Therapies: Employed in synergistic antibiotic combinations to combat multi-drug resistant pathogens.
• Hospital Compounding: Utilized in specialized pharmacy compounding for targeted patient care where commercial formulations are unsuitable.

Basic Information

Product Name	Butikacin
CAS No.	59733-86-7
Molecular Formula	C₂₁H₄₁N₅O₁₂
Molecular Weight	555.58 g/mol
Synonyms	Butikacin; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-O-(3-amino-3-deoxy-α-D-glucopyranosyl)kanamycin A; 1-N-AHB-Kanamycin A; Butikacina; Butikacinum; Antibiotic 44729; UK-44729
EINECS	Contact for details

Quality Control

Our Butikacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	+112° to +118° (c=1 in H₂O)
pH (1% solution)	5.5 - 7.5
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.