Description

H-Ile-Gln-Oh CAS NO 59652-60-7 is a high-purity, protected dipeptide building block essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise molecular control in the development of novel therapeutic peptides and biochemical tools. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for applications ranging from drug discovery to the study of protein structure and function.

Application

• Pharmaceutical Intermediates: A key raw material in the solid-phase and solution-phase synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a building block for constructing custom peptide sequences to study enzyme-substrate interactions, receptor binding, and metabolic pathways.
• Drug Discovery & Development: Integral in medicinal chemistry for creating peptide libraries and optimizing lead compounds for enhanced potency, selectivity, and stability.
• Cosmeceutical Peptides: Serves as a precursor in the synthesis of bioactive peptides for advanced skincare formulations targeting specific dermatological benefits.
• Diagnostic Reagent Synthesis: Employed in the production of labeled peptides and probes used in immunoassays and diagnostic kits.

Basic Information

Product Name	H-Ile-Gln-Oh
CAS No.	59652-60-7
Molecular Formula	C11H21N3O4
Molecular Weight	259.30 g/mol
Synonyms	Isoleucyl-glutamine; H-Ile-Gln-OH; L-Isoleucyl-L-glutamine; ILE-GLN; N-(L-Isoleucyl)-L-glutamine; (2S)-2-[[(2S)-2-Amino-3-methylpentanoyl]amino]-4-carbamoylbutanoic acid; L-Glutamine, N-L-isoleucyl-; Fmoc-Ile-Gln(Trt)-OH (protected form precursor)
EINECS	Contact for details

Quality Control

Our H-Ile-Gln-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and MS. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Specific range available on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.