Description

H-Ile-Asn-Oh CAS NO 59652-59-4 is a protected dipeptide derivative, specifically the C-terminal carboxylic acid of the isoleucine-asparagine sequence. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptides and proteins. It is primarily utilized by pharmaceutical researchers and biotech companies developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediates: Key raw material for the synthesis of therapeutic peptides targeting metabolic disorders, oncology, and cardiovascular diseases.
• Biochemical Research: Used as a custom peptide fragment in academic and industrial R&D for studying protein-protein interactions and enzyme mechanisms.
• Peptide Library Construction: Essential component in combinatorial chemistry for generating diverse peptide libraries for drug discovery screening.
• API Development: Intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for peptide-based drugs.
• Diagnostic Reagent Synthesis: Building block for labeled peptides used in immunoassays and molecular imaging probes.
• Cosmeceutical Peptides: Potential ingredient in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	H-Ile-Asn-Oh
CAS No.	59652-59-4
Molecular Formula	C13H23N3O5
Molecular Weight	301.34 g/mol
Synonyms	Isoleucyl-Asparagine; H-Ile-Asn-OH; Ile-Asn; L-Isoleucyl-L-asparagine; N-(2-Amino-3-methylpentanoyl)-L-asparagine; (2S)-2-[[(2S,3S)-2-Amino-3-methylpentanoyl]amino]-3-carbamoylpropanoic acid; Fmoc-Ile-Asn(Trt)-OH (protected form precursor); Z-Ile-Asn-OH (protected form precursor)
EINECS	Contact for details

Quality Control

Every batch of H-Ile-Asn-Oh is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for peptide synthesis. Our products undergo rigorous quality testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.