Description

2-Methylarginine is a non-proteinogenic amino acid derivative of L-arginine, featuring a methyl group substitution. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex peptides and pharmaceutical compounds. It is primarily utilized by research institutions and manufacturers in the life sciences, pharmaceutical development, and fine chemical synthesis sectors.

Application

• Biochemical Research: Used as a reference standard, enzyme substrate, or inhibitor in studies of nitric oxide synthase (NOS) and other arginine-metabolizing pathways.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel peptide-based therapeutics and drug candidates.
• Proteomics & Metabolomics: Employed in mass spectrometry and analytical workflows for method development and as an internal standard.
• Nutritional Science Research: Investigated for its potential role and effects in amino acid metabolism studies.
• Fine Chemical Synthesis: Acts as a chiral synthon for the preparation of specialized compounds requiring modified arginine structures.

Basic Information

Product Name	2-Methylarginine
CAS No.	59574-26-4
Molecular Formula	C7H16N4O2
Molecular Weight	188.23 g/mol
Synonyms	NG-Methyl-L-arginine; L-NG-Methylarginine; MMA; NG-Methylarginine; 2-Amino-5-[(methylamino)iminomethyl]aminopentanoic acid; (S)-2-Amino-5-[(methylamino)iminomethyl]aminopentanoic acid; N-Methyl-L-arginine; ω-N-Methyl-L-arginine
EINECS	Contact for details

Quality Control

Our 2-Methylarginine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with detailed results for traceability and assurance. Specifications can meet the requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.