Description

2-Pyrimidineacetonitrile (9Ci) is a versatile heterocyclic nitrile building block, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in its reactive cyanoethyl group attached to the pyrimidine ring, enabling the construction of complex molecular architectures. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create specialized pyrimidine-based ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic activity and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Pyrimidineacetonitrile (9Ci)
CAS No.	59566-45-9
Molecular Formula	C6H5N3
Molecular Weight	119.12 g/mol
Synonyms	2-(Cyanomethyl)pyrimidine; Pyrimidine-2-acetonitrile; 2-Pyrimidylacetonitrile; (Pyrimidin-2-yl)acetonitrile; 2-Pyrimidineacetonitrile; α-Pyrimidineacetonitrile; 59566-45-9 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Pyrimidineacetonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our quality commitment supports compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.