Description

5-Bromo-2-Chloro-4-(Methylthio)Pyrimidine is a high-purity halogenated pyrimidine derivative, a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo, chloro, and methylthio functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral, anticancer, and other biologically active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a versatile building block for creating libraries of novel pyrimidine-based compounds for screening.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production of client-specific molecules.

Basic Information

Product Name	5-Bromo-2-Chloro-4-(Methylthio)Pyrimidine
CAS No.	59549-51-8
Molecular Formula	C5H4BrClN2S
Molecular Weight	239.52 g/mol
Synonyms	5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine; 4-(Methylthio)-5-bromo-2-chloropyrimidine; 2-Chloro-5-bromo-4-methylthiopyrimidine; 5-Bromo-2-chloro-4-methylsulfanylpyrimidine; 59549-51-8; Pyrimidine, 5-bromo-2-chloro-4-(methylthio)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-(Methylthio)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks, and specifications can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.