Description

4-Amino-3 5-Diiodo-L-Phenylalanine is a halogenated derivative of the essential amino acid L-phenylalanine, characterized by the presence of two iodine atoms and an amino group on the aromatic ring. This unique structure makes it a valuable non-natural amino acid and a critical synthetic intermediate for the development of novel bioactive compounds. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced drug discovery and biochemical research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of thyroid hormone analogs, radiopharmaceuticals, and other iodine-containing therapeutic agents.
• Biochemical Research: Used as a specialized precursor or substrate in enzymatic studies, metabolic pathway investigations, and protein engineering.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) or to create peptides with modified properties for diagnostic or therapeutic applications.
• Radiology & Imaging: Serves as a precursor for compounds used in medical imaging, leveraging the iodine atoms for contrast or radiolabeling purposes.
• Organic Synthesis: Employed as a versatile intermediate in organic chemistry for the construction of complex molecules with specific halogenated aromatic motifs.

Basic Information

Product Name	4-Amino-3 5-Diiodo-L-Phenylalanine
CAS No.	59515-83-2
Molecular Formula	C9H10I2N2O2
Molecular Weight	447.99 g/mol
Synonyms	3,5-Diiodo-4-amino-L-phenylalanine; L-4-Amino-3,5-diiodophenylalanine; 4-Amino-3,5-diiodo-L-phenylalanine; (2S)-2-Amino-3-(4-amino-3,5-diiodophenyl)propanoic acid; 3,5-Diiodo-4-aminophenylalanine; DIH; 4-Amino-3,5-diiodo-DL-phenylalanine (racemic mixture); 59515-83-2
EINECS	Contact for details

Quality Control

Our 4-Amino-3 5-Diiodo-L-Phenylalanine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range upon request
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.