Description

H-Ala-Leu-OMe HCl is a protected dipeptide derivative, specifically the methyl ester hydrochloride salt of the alanine-leucine sequence. This compound serves as a crucial building block in peptide synthesis, offering controlled reactivity for the sequential assembly of longer, more complex peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biochemical sectors for drug discovery, proteomics research, and the development of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, stepwise construction of custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Tool Development: Employed to synthesize peptide substrates, inhibitors, or standards for enzymatic assays and diagnostic applications.
• Academic & Industrial R&D: A fundamental reagent for exploring peptide structure-activity relationships (SAR) and new synthetic methodologies.
• Production of Longer Peptides: Acts as a dimer unit to efficiently introduce the Ala-Leu segment into larger polypeptides and proteins.

Basic Information

Product Name	H-Ala-Leu-OMe HCl
CAS No.	59515-79-6
Molecular Formula	C10H21N2O3 • HCl
Molecular Weight	268.75 g/mol
Synonyms	L-Alanyl-L-leucine methyl ester hydrochloride; Alanine-Leucine methyl ester HCl; H-Ala-Leu-OMe hydrochloride; Methyl L-alanyl-L-leucinate hydrochloride; Ala-Leu-OMe • HCl; L-Ala-L-Leu-OMe • HCl; N-(L-Alanyl)-L-leucine methyl ester hydrochloride; Peptide synthesis building block 59515-79-6
EINECS	Contact for details

Quality Control

Our H-Ala-Leu-OMe HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and identity confirmation by IR and NMR. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.