Description

Boc-Met-Enkephalin is a protected synthetic peptide derivative of the endogenous opioid peptide methionine-enkephalin. This compound is a critical intermediate in peptide synthesis, specifically designed for research and development within the pharmaceutical and biochemical sectors. It is primarily utilized by scientists and manufacturers engaged in neurobiological research, analgesic drug discovery, and the production of specialized peptide-based reagents.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of enkephalin analogs and related opioid peptides for pharmacological studies.
• Neuroscience Research: Used as a precursor in studies investigating opioid receptor binding, signal transduction pathways, and the physiological role of enkephalins.
• Analgesic Drug Development: Serves as a starting material for creating novel peptide-based candidates with potential analgesic properties and improved metabolic stability.
• Biochemical Tool Compound: Employed in the preparation of labeled (e.g., fluorescent, radioactive) peptides for assay development and receptor mapping.
• Academic & Institutional Research: Essential reagent for universities and research institutes focusing on peptide chemistry, neuropharmacology, and medicinal chemistry.

Basic Information

Product Name	Boc-Met-Enkephalin
CAS No.	59481-77-5
Molecular Formula	C33H45N5O9S
Molecular Weight	687.81 g/mol
Synonyms	Boc-Tyr-Gly-Gly-Phe-Met-OH; N-tert-Butoxycarbonyl-methionine-enkephalin; Boc-Met-Enk; Boc-Met5-Enkephalin; Boc-Enkephalin, Methionine-; tert-Butyloxycarbonyl-Methionine Enkephalin; H-Tyr-Gly-Gly-Phe-Met-OH, Nα-Boc protected; Nα-Boc-L-tyrosylglycylglycyl-L-phenylalanyl-L-methionine
EINECS	Contact for details

Quality Control

Our Boc-Met-Enkephalin is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substance profiles. While produced to meet high standards for research chemicals, we can discuss custom synthesis to align with specific project requirements or preliminary GMP guidelines for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.