Description

[Tyr11]-Somatostatin is a synthetic peptide analog of the endogenous neurohormone somatostatin, featuring a tyrosine substitution at the 11th position. This modification is significant for research into receptor binding affinity and metabolic regulation studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology and oncology.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of somatostatin receptor (SSTR) subtypes, particularly SSTR2 and SSTR5.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the development of novel peptide-based therapeutics for hormonal disorders and cancers.
• Biochemical Assays: Employed in competitive binding assays, radioimmunoassays (RIA), and enzyme-linked immunosorbent assays (ELISA) to study hormone inhibition.
• Metabolic Studies: Applied in preclinical research to investigate the regulation of growth hormone (GH), insulin, and glucagon secretion.
• Academic & Clinical Research: Supports fundamental research in neuroendocrinology, gastroenterology, and oncology for understanding peptide hormone pathways.

Basic Information

Product Name	[Tyr11]-Somatostatin
CAS No.	59481-27-5
Molecular Formula	C76H104N18O19S2
Molecular Weight	1637.9 g/mol
Synonyms	Tyr11-Somatostatin-14; Somatostatin (5-Tyrosine); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14); SRIF-14 (Tyr11); Tyr11-SRIF; Growth Hormone Release-Inhibiting Hormone (5-Tyrosine)
EINECS	Contact for details

Quality Control

Our [Tyr11]-Somatostatin is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.