Description

Ac-Muramyl-Ala-Glu-Nh2 is a synthetic muramyl dipeptide (MDP) derivative, a key structural component of bacterial peptidoglycan. This compound is of significant interest for its role as a potent immunomodulator and adjuvant in immunological research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in vaccine development, immunology studies, and the synthesis of novel immunostimulatory agents.

Application

• Immunological Research: Used as a reference standard and active component in studies of innate immune response, particularly through NOD2 receptor activation.
• Vaccine Adjuvant Development: Serves as a synthetic analog for formulating and testing novel vaccine adjuvants to enhance immune response.
• Pharmaceutical Intermediates: Acts as a key building block in the synthesis of more complex immunomodulatory compounds and prodrugs.
• Biochemical Reagent: Employed in cell-based assays and in vitro studies to investigate inflammatory pathways and cytokine production.
• Peptide Synthesis: Used as a specialized amino acid derivative in solid-phase or solution-phase peptide synthesis for creating custom immunogenic sequences.

Basic Information

Product Name	Ac-Muramyl-Ala-Glu-Nh2
CAS No.	59331-38-3
Molecular Formula	C22H36N4O12
Molecular Weight	548.54 g/mol
Synonyms	N-Acetylmuramyl-L-alanyl-D-isoglutamine; MDP (Muramyl Dipeptide); Ac-MDP; N-Acetylmuramyl-Ala-D-Glu-NH2; L-Ala-D-isoGln MDP; Adjuvant Peptide; Murametide; Nor-MDP Ac; NSC 324366
EINECS	Contact for details

Quality Control

Our Ac-Muramyl-Ala-Glu-Nh2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and chiral purity analysis to ensure the correct stereochemistry. Certificates of Analysis (COA) detailing all specifications are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Optical Rotation	Specific range available on COA
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.