Description

n-Acetyl-3-Iodo-L-Tyrosine, Amide is a specialized iodinated tyrosine derivative, a key building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a precursor in the development of novel bioactive molecules, particularly those targeting thyroid hormone pathways and receptor-specific agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in peptide modification, radiopharmaceutical development, and the synthesis of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of thyroid hormone analogs and receptor modulators.
• Peptide Chemistry Research: Used for the site-specific iodination and modification of tyrosine residues in peptide sequences to study structure-activity relationships.
• Radiopharmaceutical Development: Serves as a non-radioactive reference standard and a synthetic precursor for iodine-123 or iodine-131 labeled compounds used in diagnostic imaging.
• Biochemical Probe Synthesis: Employed in creating labeled probes for studying enzyme kinetics, particularly tyrosine kinases and phosphatases.
• Fine Chemical Synthesis: A versatile building block for constructing complex molecules in medicinal chemistry and agrochemical research.

Basic Information

Product Name	n-Acetyl-3-Iodo-L-Tyrosine, Amide
CAS No.	59302-19-1
Molecular Formula	C11H13IN2O3
Molecular Weight	348.14 g/mol
Synonyms	N-Acetyl-3-iodo-L-tyrosinamide; 3-Iodo-N-acetyl-L-tyrosinamide; L-Tyrosinamide, N-acetyl-3-iodo-; Acetyl-3-iodotyrosine amide; (2S)-2-Acetamido-3-(4-hydroxy-3-iodophenyl)propanamide; 3-Iodo-Nα-acetyl-L-tyrosinamide; N-Acetyl-3-iodotyrosinamide
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Iodo-L-Tyrosine, Amide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a Certificate of Analysis (COA) with each shipment, detailing all critical specifications to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.