Description

(2R,3S)-2-Amino-3-Hydroxy-Hexanoic Acid is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 2 and 3 positions. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals and bioactive molecules. It is particularly valuable for research and development in medicinal chemistry, peptide synthesis, and as a precursor for novel therapeutic agents targeting metabolic and neurological pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antibiotics, and other active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the solid-phase and solution-phase synthesis of modified peptides to study structure-activity relationships.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(2R,3S)-2-Amino-3-Hydroxy-Hexanoic Acid
CAS No.	59286-25-8
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2R,3S)-2-Amino-3-hydroxycaproic acid; (2R,3S)-3-Hydroxy-L-norleucine; allo-Threonine, 3-ethyl-; L-2-Amino-3-hydroxyhexanoic acid; 2-Amino-3-hydroxyhexanoic acid (2R,3S)-isomer; Norleucine, 3-hydroxy-, (2R,3S)-; UNII-9K5N8V2C8Q
EINECS	Contact for details

Quality Control

Our (2R,3S)-2-Amino-3-Hydroxy-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.