Description

n-Acetylmuramyl-Alanyl-Isoglutaminyl-Lysine is a synthetic muramyl dipeptide (MDP) derivative, a key structural motif found in bacterial peptidoglycan. This compound is of significant interest for its role as a potent immunomodulator and adjuvant, capable of stimulating the innate immune system. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for vaccine development, immunology studies, and as a reference standard.

Application

• Immunological Research: Used as a reference standard and active component in studies of innate immunity, NOD2 receptor signaling, and inflammatory pathways.
• Vaccine Adjuvant Development: Investigated for enhancing the efficacy of vaccines by boosting immune responses, particularly for subunit and peptide-based vaccines.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate in the production of more complex immunostimulatory compounds and drug candidates.
• Biochemical Tool: Employed in cell culture and in vitro assays to study macrophage activation, cytokine production, and host-pathogen interactions.
• Quality Control & Standardization: Used as a high-purity analytical standard in QC laboratories for method development and validation in related pharmaceutical processes.

Basic Information

Product Name	n-Acetylmuramyl-Alanyl-Isoglutaminyl-Lysine
CAS No.	59275-09-1
Molecular Formula	C24H41N7O12
Molecular Weight	619.62 g/mol
Synonyms	MDP-Lys; MDP-Lysine; Muramyl Dipeptide-Lysine; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-L-lysine; L-Ala-D-isoGln-L-Lys(MDP); Ac-MurNAc-L-Ala-D-isoGln-L-Lys; Immunoadjuvant Peptide; 6-O-(2-Acetamido-2-deoxy-D-glucopyranosyl)-N-acetylmuramyl-L-alanyl-D-isoglutaminyl-L-lysine
EINECS	Contact for details

Quality Control

Our n-Acetylmuramyl-Alanyl-Isoglutaminyl-Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.