Description

H-Met-Pro-Oh CAS NO 59227-86-0 is a high-purity, protected dipeptide derivative featuring the amino acids methionine and proline. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise construction of complex peptide sequences for research and therapeutic applications. It is essential for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing novel peptide-based drugs, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of therapeutic peptides targeting metabolic disorders, cardiovascular diseases, and oncology.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected fragment for the efficient, sequential assembly of custom peptide chains.
• Biochemical Research: Employed in structure-activity relationship (SAR) studies to investigate peptide function and receptor interactions.
• API Development: A crucial precursor in the development and scale-up of Active Pharmaceutical Ingredients (APIs) for clinical trials.
• Peptide Library Construction: Facilitates the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Cosmeceutical Peptides: Potential ingredient in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	H-Met-Pro-Oh
CAS No.	59227-86-0
Molecular Formula	C11H20N2O3S
Molecular Weight	260.35 g/mol
Synonyms	Methionylproline; H-Met-Pro-OH; L-Methionyl-L-proline; Methionine-Proline; N-(Methoxycarbonyl)methionylproline; Boc-Met-Pro-OH (related protected form); Fmoc-Met-Pro-OH (related protected form); L-Met-L-Pro
EINECS	Contact for details

Quality Control

Our H-Met-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric purity, and identity confirmation via IR and MS. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and cGMP-grade standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.