Description

4-Piperazin-1-Ylquinazoline is a high-purity, heterocyclic organic compound featuring a quinazoline core substituted with a piperazine moiety. This specific molecular architecture makes it a valuable pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. The compound, identified by CAS NO 59215-41-7, is supplied to meet the stringent demands of modern medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis: Used in the preparation of more complex heterocyclic compounds due to its reactive quinazoline and secondary amine functionalities.
• Biochemical Research: May be employed as a tool compound or ligand in biochemical assays to study enzyme interactions and biological pathways.
• Fine Chemical Production: Integrated into multi-step synthesis processes for the manufacture of specialty chemicals with specific biological or material properties.

Basic Information

Product Name	4-Piperazin-1-Ylquinazoline
CAS No.	59215-41-7
Molecular Formula	C₁₂H₁₄N₄
Molecular Weight	214.27 g/mol
Synonyms	4-(Piperazin-1-yl)quinazoline; Quinazoline, 4-(1-piperazinyl)-; 4-(1-Piperazinyl)quinazoline; 1-(Quinazolin-4-yl)piperazine; 4-Piperazinylquinazoline; 4-Quinazolinylpiperazine; 59215-41-7
EINECS	Contact for details

Quality Control

Our 4-Piperazin-1-Ylquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.