Description

5-Methoxy-2-(Piperazin-1-yl)pyrimidine is a versatile heterocyclic building block featuring a pyrimidine core substituted with a methoxy group and a piperazine moiety. This molecular structure makes it a critical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a building block for creating new pesticides, herbicides, and fungicides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: The piperazine nitrogen atoms can be utilized to coordinate metals or form complexes for catalytic applications.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or functional polymers.

Basic Information

Product Name	5-Methoxy-2-(Piperazin-1-yl)pyrimidine
CAS No.	59215-39-3
Molecular Formula	C9H14N4O
Molecular Weight	194.24 g/mol
Synonyms	5-Methoxy-2-(1-piperazinyl)pyrimidine; 2-(Piperazin-1-yl)-5-methoxypyrimidine; 5-Methoxy-2-piperazin-1-ylpyrimidine; 59215-39-3; 1-(5-Methoxypyrimidin-2-yl)piperazine; 5-Methoxy-2-(piperazin-1-yl)pyrimidine; 5-Methoxy-2-piperazin-1-yl-pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-(Piperazin-1-yl)pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.