Description

2-Bromo-4-Fluorobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Bromo-4-Fluorobenzaldehyde
CAS No.	59142-68-6
Molecular Formula	C7H4BrFO
Molecular Weight	203.01 g/mol
Synonyms	4-Fluoro-2-bromobenzaldehyde; 2-Bromo-4-fluorobenzenecarboxaldehyde; Benzenecarboxaldehyde, 2-bromo-4-fluoro-; 4-Fluoro-o-bromobenzaldehyde; o-Bromo-p-fluorobenzaldehyde; 2-Bromo-4-fluorobenzaldehyde (primary IUPAC); 2-Bromo-4-fluorophenyl aldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.