Description

Proinsulin C-Peptide is a biologically significant peptide fragment cleaved from proinsulin during the production of insulin. It serves as a critical marker for endogenous insulin secretion and is essential for research into diabetes mellitus and metabolic disorders. This high-purity peptide is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on endocrinology and peptide therapeutics.

Application

• Biomedical Research: Fundamental studies on insulin biosynthesis, processing, and secretion mechanisms.
• Diabetes Diagnostics: Used as a reference standard in immunoassays to measure C-peptide levels, which differentiate endogenous insulin production from exogenous insulin administration.
• Therapeutic Development: Investigation into the potential therapeutic effects of C-peptide on diabetic complications, including neuropathy and nephropathy.
• Quality Control Standard: Serves as a critical reference material for the calibration and validation of analytical methods in pharmaceutical quality control labs.
• Clinical Study Reagent: Employed in clinical research to assess β-cell function in patients with type 1 or type 2 diabetes.

Basic Information

Product Name	Proinsulin C-Peptide
CAS No.	59112-80-0
Molecular Formula	C₁₁₂H₁₇₉N₃₅O₄₉S
Molecular Weight	3020.3 g/mol
Synonyms	Human C-Peptide; Proinsulin Connecting Peptide; Insulin C-Peptide; C-Peptide (Human); C-Peptide I (Human); C-Peptide (31 AA); H-CPEP; Connecting Peptide
EINECS	Contact for details

Quality Control

Our Proinsulin C-Peptide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.