Description

6-Fluorodopamine is a fluorinated derivative of the key neurotransmitter dopamine, distinguished by the substitution of a fluorine atom at the 6-position of the catechol ring. This structural modification significantly alters its biological activity and metabolic stability, making it a critical research compound in neuroscience and pharmacology. It is primarily utilized by pharmaceutical R&D teams and academic researchers for investigating dopaminergic systems, developing neuroimaging agents, and exploring novel therapeutic pathways.

Application

• Neuroscience Research: As a biochemical tool for studying dopamine receptor binding, uptake, and release mechanisms.
• Radiopharmaceutical Development: A precursor for the synthesis of fluorine-18 labeled tracers used in Positron Emission Tomography (PET) imaging of the brain.
• Pharmacological Studies: Used to investigate the structure-activity relationships (SAR) of catecholamine analogs and their effects on the central nervous system.
• Metabolic Pathway Analysis: Employed to trace and understand the metabolic fate of fluorinated neurotransmitters.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical development and forensic analysis.

Basic Information

Product Name	6-Fluorodopamine
CAS No.	59043-70-8
Molecular Formula	C8H10FNO2
Molecular Weight	171.17 g/mol
Synonyms	6-FDA; 2-(3,4-Dihydroxyphenyl)-1-fluoroethanamine; 4-(2-Aminoethyl)-5-fluorobenzene-1,2-diol; 6-Fluorodopamine Hydrochloride (salt form); 6-Fluoro-3,4-dihydroxyphenethylamine; 6-Fluoro-DA; 1-(3,4-Dihydroxyphenyl)-2-fluoroethanamine
EINECS	Contact for details

Quality Control

Our 6-Fluorodopamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by HPLC, NMR, and mass spectrometry. We adhere to cGMP guidelines for the production of research-grade fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.