Description

H-Phe-Gly-Phe-Gly-Oh is a synthetic tetrapeptide sequence featuring alternating phenylalanine and glycine residues. This compound is of significant interest in biochemical research and pharmaceutical development due to its utility as a model peptide for studying enzyme kinetics, molecular recognition, and as a building block for more complex peptide structures. It serves as a critical intermediate for researchers and manufacturers in the life sciences, biotechnology, and pharmaceutical sectors who require high-purity, well-characterized peptide fragments.

Application

• Pharmaceutical Intermediate: Used as a key building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Serves as a model substrate for studying protease (e.g., elastase, chymotrypsin) activity, specificity, and inhibition kinetics.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the relationship between peptide sequence, conformation, and biological function.
• Peptide Library Synthesis: Acts as a core scaffold or spacer in the combinatorial synthesis of peptide libraries for drug discovery screening.
• Academic & Industrial R&D: Utilized in fundamental research on peptide folding, aggregation, and biomaterial development.
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in peptide analysis.

Basic Information

Product Name	H-Phe-Gly-Phe-Gly-Oh
CAS No.	59005-83-3
Molecular Formula	C22H26N4O5
Molecular Weight	426.47 g/mol
Synonyms	Phe-Gly-Phe-Gly; FGFG; L-Phenylalanyl-glycyl-L-phenylalanyl-glycine; Tetrapeptide FGFG; H-Phe-Gly-Phe-Gly-OH; Phenylalanine-Glycine-Phenylalanine-Glycine; N-(N-(N-L-Phenylalanylglycyl)-L-phenylalanyl)glycine; Glycine, L-phenylalanylglycyl-L-phenylalanyl-
EINECS	Contact for details

Quality Control

Our H-Phe-Gly-Phe-Gly-Oh is manufactured under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and MS for identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.