Description

5-Chloro-2,4-Bis-Trimethylsilanyloxy-Pyrimidine is a key organosilicon-protected pyrimidine derivative, primarily serving as a versatile synthetic intermediate in advanced organic synthesis. Its value lies in the trimethylsilyl (TMS) protecting groups, which enhance solubility and stability, facilitating complex multi-step reactions under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of nucleoside analogs, active pharmaceutical ingredients (APIs), and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new reaction pathways in organic and medicinal chemistry laboratories.
• Material Science Research: Potential monomer or precursor for creating novel polymers and functional materials with specific electronic properties.

Basic Information

Product Name	5-Chloro-2,4-Bis-Trimethylsilanyloxy-Pyrimidine
CAS No.	58990-53-7
Molecular Formula	C10H19ClN2O2Si2
Molecular Weight	290.90 g/mol
Synonyms	5-Chloro-2,4-bis(trimethylsiloxy)pyrimidine; 5-Chloro-2,4-bis(trimethylsilyloxy)pyrimidine; 2,4-Bis-O-(trimethylsilyl)-5-chloropyrimidine; 5-Chloro-2,4-pyrimidinediol bis(trimethylsilyl) ether; Pyrimidine, 5-chloro-2,4-bis(trimethylsiloxy)-; 5-Chloro-2,4-di-O-trimethylsilylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4-Bis-Trimethylsilanyloxy-Pyrimidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.