Description

n-Dodecanoyl-L-Proline is a high-purity, synthetic amino acid derivative where a dodecanoyl (lauroyl) chain is conjugated to the L-proline moiety. This molecular design is significant for its role as a key intermediate in the synthesis of advanced pharmaceutical compounds and as a building block for specialized peptides. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting enzyme inhibition.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Peptide Synthesis: Serves as a modified amino acid residue for constructing specialized peptides with enhanced lipophilicity or specific bioactivity.
• Cosmetic Ingredient: Potential use in high-end skincare formulations as a peptide derivative for its skin-conditioning properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for labeling and studying protein function and interactions.

Basic Information

Product Name	n-Dodecanoyl-L-Proline
CAS No.	58725-39-6
Molecular Formula	C₁₇H₃₁NO₃
Molecular Weight	297.43 g/mol
Synonyms	L-Proline, 1-(1-oxododecyl)-; 1-Lauroyl-L-proline; Dodecanoyl-L-proline; Lauroylproline; (S)-1-(1-Oxododecyl)pyrrolidine-2-carboxylic Acid; N-Dodecanoylproline; N-Lauroyl-L-proline; Proline, N-lauroyl-, L-
EINECS	Contact for details

Quality Control

Our n-Dodecanoyl-L-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting standards for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.