Description

Melittin(8-26) is a defined peptide fragment derived from the primary toxin found in honey bee venom. This compound is of significant interest in biochemical and pharmacological research due to its role in studying the structure-activity relationship of the full melittin peptide. It is primarily utilized by research institutions and pharmaceutical development companies focusing on peptide chemistry, membrane biology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and tool peptide for studying the properties and mechanisms of melittin.
• Structure-Activity Relationship (SAR) Studies: Critical for investigating which segments of the full melittin peptide are responsible for its hemolytic and antimicrobial activities.
• Membrane Interaction Studies: Employed in biophysical research to understand how peptides interact with and disrupt lipid bilayers and cell membranes.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the R&D of peptide-based drugs and antimicrobial agents.
• Academic Laboratories: Used in university and institutional research for teaching and advanced studies in peptide synthesis and toxicology.

Basic Information

Product Name	Melittin(8-26)
CAS No.	58672-95-0
Molecular Formula	C89H147N27O24
Molecular Weight	1999.3 g/mol
Synonyms	Melittin fragment 8-26; Bee Venom Peptide (8-26); H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2; Melittin (8-26) amide; [8-26]-Melittin
EINECS	Contact for details

Quality Control

Our Melittin(8-26) is produced and analyzed under strict quality management protocols. Each batch undergoes comprehensive testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full transparency and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.