Description

α-Ketoglutaric Acid Monopotassium Salt is a key biochemical intermediate and a stable, water-soluble salt form of α-ketoglutaric acid. This compound is essential in cellular metabolism, serving as a critical substrate in the Krebs cycle and nitrogen metabolism. It is primarily utilized in the formulation of cell culture media, diagnostic reagents, and as a precursor in the synthesis of various pharmaceuticals and nutraceuticals.

Application

• Cell Culture & Fermentation: A vital component in mammalian and microbial cell culture media, supporting cell growth and protein production.
• Diagnostic Reagents: Used in clinical diagnostic kits for the enzymatic determination of transaminases (ALT, AST) in blood serum.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of certain amino acids and other active pharmaceutical ingredients (APIs).
• Nutraceuticals & Sports Nutrition: Incorporated into dietary supplements for its potential role in supporting energy metabolism and athletic performance.
• Biochemical Research: Employed as a standard or substrate in enzymatic assays and metabolic pathway studies within research laboratories.
• Plant Tissue Culture: Acts as a carbon source and metabolic intermediate in media for plant cell and tissue culture applications.

Basic Information

Product Name	α-Ketoglutaric Acid Monopotassium Salt
CAS No.	58485-42-0
Molecular Formula	C5H7KO5
Molecular Weight	186.21 g/mol
Synonyms	2-Oxoglutaric Acid Monopotassium Salt; 2-Oxopentanedioic Acid Monopotassium Salt; α-Ketoglutaric Acid Potassium Salt; Potassium 2-Oxoglutarate; Potassium α-Ketoglutarate; AKG Monopotassium Salt; Oxoglutaric Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our α-Ketoglutaric Acid Monopotassium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, heavy metals, and microbiological limits, supporting applications in research, diagnostics, and cGMP manufacturing where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (5% solution)	3.0 - 5.0
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Microbiological Control	Total Plate Count < 1000 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.