Description

4-Ethyl Hydrogen L-Aspartate Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled introduction of the L-aspartate moiety into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptides, prodrugs, and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate protected aspartic acid residues.
• Prodrug Development: Serves as a precursor for designing ester-based prodrugs to enhance drug solubility and bioavailability.
• Biochemical Research: Employed in studies of enzyme substrates, metabolic pathways, and amino acid derivatives.
• Fine Chemical Synthesis: A valuable intermediate for creating specialized compounds in agrochemical and material science research.

Basic Information

Product Name	4-Ethyl Hydrogen L-Aspartate Hydrochloride
CAS No.	58485-25-9
Molecular Formula	C6H11NO4 • HCl
Molecular Weight	197.62 g/mol
Synonyms	L-Aspartic acid 4-ethyl ester hydrochloride; H-Asp(OEt)-OH • HCl; (S)-2-Amino-4-ethoxy-4-oxobutanoic acid hydrochloride; 4-Ethyl L-aspartate hydrochloride; Aspartic acid β-ethyl ester hydrochloride; Ethyl hydrogen L-aspartate hydrochloride; (2S)-2-Azaniumyl-4-ethoxy-4-oxobutanoate chloride
EINECS	Contact for details

Quality Control

Our 4-Ethyl Hydrogen L-Aspartate Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, enantiomeric purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.