Description

n-n-Propylnorapomorphine is a synthetic aporphine derivative, a potent and selective dopamine receptor agonist of significant research interest. Its unique pharmacological profile makes it a critical reference standard and active pharmaceutical ingredient (API) intermediate in advanced neuroscience and medicinal chemistry studies. This compound is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on central nervous system (CNS) disorders, neurodegenerative disease models, and receptor characterization.

Application

• Pharmacological Research: Used as a high-affinity dopamine D1 and D2 receptor agonist in neuropharmacology studies.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Medicinal Chemistry: Acts as a key synthetic intermediate or lead compound for the development of novel therapeutics targeting Parkinson's disease and related movement disorders.
• Neuroscience Studies: Employed in *in vitro* and *in vivo* models to investigate dopaminergic pathways, neuronal signaling, and behavioral responses.
• API Development: Utilized in the synthesis and pre-clinical development of potential new chemical entities (NCEs) for CNS applications.

Basic Information

Product Name	n-n-Propylnorapomorphine
CAS No.	58479-52-0
Molecular Formula	C18H21NO2
Molecular Weight	283.37 g/mol
Synonyms	N-Propylnorapomorphine; 10,11-Dimethoxy-6aβ-aporphine-7α-ol; (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol; N-Propylnoraporphine; R-(–)-N-n-Propylnorapomorphine; (–)-NPA; NPA
EINECS	Contact for details

Quality Control

Our n-n-Propylnorapomorphine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by high-performance liquid chromatography (HPLC). We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.