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2-Bromo-6-(Trifluoromethyl)Aniline CAS NO 58458-13-2


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CAS No.:58458-13-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-6-(Trifluoromethyl)Aniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and trifluoromethyl substituents, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

  • Key pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
  • Building block for agrochemicals, including herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
  • Precursor in material science for the development of organic semiconductors, liquid crystals, and specialty polymers.
  • Versatile reagent in organic synthesis for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution.
  • Starting material for the synthesis of dyes and pigments with specific light-fastness and color properties.
  • Intermediate in the research and development of ligands and catalysts for asymmetric synthesis and coordination chemistry.

Basic Information

Product Name 2-Bromo-6-(Trifluoromethyl)Aniline
CAS No. 58458-13-2
Molecular Formula C7H5BrF3N
Molecular Weight 240.02 g/mol
Synonyms 2-Bromo-6-(trifluoromethyl)benzenamine; 2-Bromo-α,α,α-trifluoro-o-toluidine; 1-Amino-2-bromo-6-(trifluoromethyl)benzene; Benzenamine, 2-bromo-6-(trifluoromethyl)-; o-Bromo-α,α,α-trifluoroaniline; 6-Trifluoromethyl-2-bromoaniline; 2-Bromo-6-trifluoromethylaniline
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Quality Control

Our 2-Bromo-6-(Trifluoromethyl)Aniline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Light yellow to brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 40 - 44 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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