Description

Angiotensin I/II (1-5) is a bioactive peptide fragment derived from the renin-angiotensin system. This compound is a critical research tool for studying cardiovascular physiology, hypertension, and enzymatic pathways involving angiotensin-converting enzyme (ACE). It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and diagnostic manufacturers focused on metabolic and cardiovascular disease studies.

Application

• Biomedical Research: Used as a reference standard and substrate in studies of the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation.
• Enzyme Activity Assays: Serves as a specific substrate for angiotensin-converting enzyme (ACE) activity and inhibition assays, crucial for drug discovery.
• Pharmaceutical Development: Employed in the screening and development of novel antihypertensive and cardiovascular therapeutic agents.
• Diagnostic Reagent Production: Used in the formulation of calibrators and controls for immunoassays measuring angiotensin peptides.
• Metabolic Pathway Analysis: A key analyte in research investigating peptide metabolism and proteolytic processing in physiological and pathological states.
• Cell Signaling Studies: Applied in research to understand receptor binding and intracellular signaling mechanisms related to angiotensin fragments.

Basic Information

Product Name	Angiotensin I/II (1-5)
CAS No.	58442-64-1
Molecular Formula	C23H34N6O5
Molecular Weight	474.56 g/mol
Synonyms	Angiotensin (1-5); Asp-Arg-Val-Tyr-Ile; DRVYI; Angiotensin I (1-5); Angiotensin II (1-5); H-Asp-Arg-Val-Tyr-Ile-OH; L-Aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucine
EINECS	Contact for details

Quality Control

Our Angiotensin I/II (1-5) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dimethyl sulfoxide (DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.