Description

n-Benzyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a crucial advanced pharmaceutical intermediate. Its value lies in its role as a versatile scaffold for the synthesis of bioactive molecules, particularly kinase inhibitors. This high-purity building block is essential for research and development in pharmaceutical, biotechnology, and fine chemical industries focused on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the multi-step synthesis of potential drug candidates.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical entities.
• Academic Research: Utilized in universities and research institutes for exploring new chemical entities and their biological activities.

Basic Information

Product Name	n-Benzyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	58360-86-4
Molecular Formula	C₁₂H₁₁N₅
Molecular Weight	225.25 g/mol
Synonyms	4-Amino-1-benzyl-1H-pyrazolo[3,4-d]pyrimidine; 1-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; N-Benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; BPP; Pyrazolopyrimidine amine derivative; 58360-86-4; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-benzyl-
EINECS	Contact for details

Quality Control

Our n-Benzyl-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.