Description

Spermine Phosphate Hexahydrate is a high-purity, crystalline salt form of the essential polyamine spermine. This compound is critical for biochemical research and pharmaceutical development due to its role in cellular growth, proliferation, and nucleic acid stabilization. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for applications ranging from molecular biology to cell culture media supplementation.

Application

• Biochemical Research & Reagent: Used as a key reagent in studies of polyamine metabolism, DNA condensation, and protein-nucleic acid interactions.
• Cell Culture & Media Supplement: Serves as a growth-promoting factor in specialized mammalian and bacterial cell culture systems.
• Pharmaceutical Intermediates: Acts as a building block or precursor in the synthesis of more complex pharmaceutical compounds and prodrugs.
• Molecular Biology: Employed in techniques such as transfection and in vitro transcription due to its ability to condense and protect nucleic acids.
• Reference Standard: Used as a certified reference material (CRM) or analytical standard in quality control laboratories for HPLC, LC-MS, or NMR analysis.
• Enzyme Studies: Utilized as a substrate or inhibitor in enzymatic assays for polyamine oxidases and other related enzymes.

Basic Information

Product Name	Spermine Phosphate Hexahydrate
CAS No.	58298-97-8
Molecular Formula	C10H30N4 · H3PO4 · 6H2O
Molecular Weight	454.41 g/mol
Synonyms	Spermine Phosphate Salt Hexahydrate; N,N'-Bis(3-aminopropyl)-1,4-butanediamine phosphate hexahydrate; 1,5,10,14-Tetraazatetradecane phosphate hexahydrate; Spermine orthophosphate hexahydrate; SPM Phosphate; Tetramine phosphate salt
EINECS	Contact for details

Quality Control

Our Spermine Phosphate Hexahydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing batch-specific results from HPLC, NMR, and elemental analysis is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	22.0 - 26.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.