Description

D-Cysteine(Mob)-Oh is a protected derivative of the non-proteinogenic amino acid D-cysteine, featuring a methoxybenzyl (Mob) protecting group on the thiol functionality. This specific molecular architecture is critical for advanced peptide synthesis and pharmaceutical research, where precise stereochemistry and controlled reactivity are paramount. It serves as a key chiral building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, enabling the development of novel therapeutic peptides and complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) where the thiol-protected D-cysteine residue is required to prevent unwanted disulfide formation during chain assembly.
• Bioconjugation & Probe Development: Serves as a precursor for creating site-specific bioconjugates, fluorescent probes, or affinity labels due to the selectively deprotectable thiol group.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in research exploring cysteine protease mechanisms and sulfur metabolism.
• Material Science: Potential application in the synthesis of functionalized polymers or surface coatings that utilize thiol-ene click chemistry.

Basic Information

Product Name	D-Cysteine(Mob)-Oh
CAS No.	58290-34-9
Molecular Formula	C11H15NO3S
Molecular Weight	241.31 g/mol
Synonyms	D-Cysteine(Mob)-OH; (R)-2-Amino-3-(4-methoxybenzylthio)propanoic acid; D-3-(4-Methoxybenzylthio)alanine; H-D-Cys(Mob)-OH; D-Cysteine, S-(4-methoxybenzyl)-; D-Cys(Mob) free acid; D-3-[(4-Methoxyphenyl)methylthio]alanine
EINECS	Contact for details

Quality Control

Every batch of D-Cysteine(Mob)-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and GMP-grade applications, with specifications typically meeting or exceeding 98.0% HPLC purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as chiral purity, assay, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.