Description

Nabazenil is a synthetic benzodiazepine derivative with specific pharmacological activity. This high-purity compound is critical for research and development in the pharmaceutical and life sciences sectors, particularly in neuropharmacology. It is primarily utilized by researchers and manufacturers focused on central nervous system (CNS) drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method validation in drug manufacturing.
• Neuropharmacology Research: Serves as a key intermediate or active compound in preclinical studies investigating benzodiazepine receptor interactions and CNS effects.
• Metabolite Studies: Employed in the identification and quantification of drug metabolites during pharmacokinetic and ADME (Absorption, Distribution, Metabolism, and Excretion) research.
• Analytical Development: Acts as a standard for calibrating equipment and developing precise HPLC, LC-MS, or GC-MS assays in analytical laboratories.

Basic Information

Product Name	Nabazenil
CAS No.	58019-65-1
Molecular Formula	C17H14ClN3O2
Molecular Weight	327.76 g/mol
Synonyms	Nabazenil; 7-Chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-2H-1,4-benzodiazepin-2-one; 1-(Prop-2-yn-1-yl)-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ro 07-9749; RO-07-9749; RO079749
EINECS	Contact for details

Quality Control

Our Nabazenil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced chromatographic techniques, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.