Description

2-(2,2,2-Trifluoroethoxy)Aniline is a specialized aromatic amine derivative featuring a trifluoroethoxy substituent, a key intermediate in advanced organic synthesis. This compound is valued for its unique combination of an aniline moiety and a fluorinated ether group, which imparts distinct electronic and physicochemical properties to target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and charge-transporting compounds in electronic displays and lighting applications.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and surface properties.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating specialized colorants with improved fastness and performance characteristics.
• Academic & Industrial Research: Employed in methodological studies and as a reagent for introducing the 2,2,2-trifluoroethoxy functional group into various molecular scaffolds.

Basic Information

Product Name	2-(2,2,2-Trifluoroethoxy)Aniline
CAS No.	57946-60-8
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-Amino-1-(2,2,2-trifluoroethoxy)benzene; 1-Amino-2-(2,2,2-trifluoroethoxy)benzene; 2-(2,2,2-Trifluoroethoxy)benzenamine; 2-Trifluoroethoxyaniline; o-(Trifluoroethoxy)aniline; Benzenamine, 2-(2,2,2-trifluoroethoxy)-; 2-Aminophenyl 2,2,2-trifluoroethyl ether
EINECS	Contact for details

Quality Control

Our 2-(2,2,2-Trifluoroethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Light yellow to amber liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.